| Catalog No. | AT439014 |
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| Applications | ELISA |
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| Host species | Rabbit |
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| Isotype | IgG |
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| Clonality | Polyclonal |
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| Immunogen | Denosumab |
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| Target | Rabbit polyclonal to Prolia. |
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| Specificity | The product is specific for Denosumab. This antibody serves as an excellent positive control for Denosumab immunogenicity (ADA) assays. |
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| Purification | Purified by antigen affinity column. |
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| Accession | 615258-40-7 |
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| Form | Liquid |
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| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
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| Product Usage Information |
| Application |
Dilution |
| ELISA |
1:5000-1:20000 |
| IHC |
1:50-1:500 |
| WB |
1:500-1:2000 |
|
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| Stability and Storage | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
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| Background | Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface.
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| Note | For research use only. |
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