Catalog No. | AY257024 | ||||||||
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Applications | ELISA | ||||||||
Host species | Rabbit | ||||||||
Isotype | IgG | ||||||||
Clonality | Polyclonal | ||||||||
Immunogen | Rituximab | ||||||||
Target | Rabbit polyclonal to Rituxan. | ||||||||
Specificity | The product is specific for Rituximab. This antibody serves as an excellent positive control for Rituximab immunogenicity (ADA) assays. | ||||||||
Purification | Purified by antigen affinity column. | ||||||||
Accession | 174722-31-7 | ||||||||
Form | Liquid | ||||||||
Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. | ||||||||
Product Usage Information |
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Stability and Storage | The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. | ||||||||
Background | Rituximab (Rituxan) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with certain autoimmune diseases and types of cancer, such as non-Hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, idiopathic thrombocytopenic purpura, and pemphigus vulgaris. Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells. When it binds to this protein it triggers cell death. • Induction Immunosuppression in High-risk Kidney Transplant Recipients., PMID:27041548 • Acute Rejection Following Kidney Transplantation: State-of-the-Art and Future Perspectives., PMID:32520680 • Induction immunosuppressive therapies in renal transplantation., PMID:21258026 • Proteasome inhibition causes apoptosis of normal human plasma cells preventing alloantibody production., PMID:18976291 • Removal of therapeutic anti-lymphocyte antibodies from human sera prior to anti-human leukocyte antibody testing., PMID:15896799 • [Biological treatment following renal transplantation]., PMID:21877601 • Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity., PMID:12632061 • Flow cytometric assay detecting cytotoxicity against human endogenous retrovirus antigens expressed on cultured multiple sclerosis cells., PMID:23656307 • Life-threatening hemolytic anemia due to an autoanti-Pr cold agglutinin: evidence that glycophorin A antibodies may induce lipid bilayer exposure and cation permeability independent of agglutination., PMID:19843291 | ||||||||
Note | For research use only. |
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