| Catalog No. | AY257024 |
|---|
| Applications | ELISA |
|---|
| Host species | Rabbit |
|---|
| Isotype | IgG |
|---|
| Clonality |
Polyclonal |
| Immunogen |
Rituximab |
| Target |
Rabbit polyclonal to Rituxan. |
| Specificity |
The product is specific for Rituximab. This antibody serves as an excellent positive control for Rituximab immunogenicity (ADA) assays. |
| Endotoxin level |
Please contact with the lab for this information. |
| Purification |
Purified by antigen affinity column. |
| Accession |
CAS: 174722-31-7 |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
|
| Product Usage Information |
| Application |
Dilution |
| ELISA |
1:5000-1:20000 |
| IHC |
1:50-1:500 |
| WB |
1:500-1:2000 |
|
|---|
| Stability and Storage |
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles. |
| Background | Rituximab (Rituxan) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with certain autoimmune diseases and types of cancer, such as non-Hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, idiopathic thrombocytopenic purpura, and pemphigus vulgaris. Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells. When it binds to this protein it triggers cell death.
• Induction Immunosuppression in High-risk Kidney Transplant Recipients., PMID:27041548
• Acute Rejection Following Kidney Transplantation: State-of-the-Art and Future Perspectives., PMID:32520680
• Induction immunosuppressive therapies in renal transplantation., PMID:21258026
• Proteasome inhibition causes apoptosis of normal human plasma cells preventing alloantibody production., PMID:18976291
• Removal of therapeutic anti-lymphocyte antibodies from human sera prior to anti-human leukocyte antibody testing., PMID:15896799
• [Biological treatment following renal transplantation]., PMID:21877601
• Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity., PMID:12632061
• Flow cytometric assay detecting cytotoxicity against human endogenous retrovirus antigens expressed on cultured multiple sclerosis cells., PMID:23656307
• Life-threatening hemolytic anemia due to an autoanti-Pr cold agglutinin: evidence that glycophorin A antibodies may induce lipid bilayer exposure and cation permeability independent of agglutination., PMID:19843291
|
|---|
| Note |
For research use only. |
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