Anti-Human IMMT Polyclonal Antibody (HS889014)

Name: Anti-Human IMMT Polyclonal Antibody
Brand: abinScience
SKU: HS889014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HS889014

Description

Anti-Human IMMT Polyclonal Antibody (HS889014) is a rabbit polyclonal antibody detecting IMMT in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human IMMT (Ala489-Glu758).

Target

p87/89, Mitofilin, Mitochondrial inner membrane protein, IMMT, HMP, MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, MIC60, MINOS2

Purification

Purified by antigen affinity column.

Accession

Q16891

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

MICOS complex subunit MIC60 (IMMT) is a ~83 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.

1. Alkhaja, AK. et al. (2012) Molecular biology of the cell 23, 247-57. PMID: 22114354

2. Ott, C. et al. (2015) PloS one 10, e0120213. PMID: 25781180

3. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732

4. Hu, C. et al. (2020) Cell death & disease 11, 940. PMID: 33130824

Note

For research use only.

Images

References

Datasheet

Anti-Human IMMT Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human IMMT Polyclonal Antibody (HS889014)

Overview

Images

References

Datasheet

SDS

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