

| Catalog No. | HP397014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human FERMT2 Polyclonal Antibody (HP397014) is a rabbit polyclonal antibody detecting FERMT2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Danio rerio.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human FERMT2 (Pro373-Lys497). | ||||||||
| Target | PLEKHC1, Mitogen-inducible gene 2 protein, Pleckstrin homology domain-containing family C member 1, Fermitin family homolog 2, PH domain-containing family C member 1, MIG-2, KIND2, FERMT2, MIG2, Kindlin-2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q96AC1 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Fermitin family homolog 2 (FERMT2) is a ~77 kDa protein. Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. | ||||||||
| Note | For research use only. |
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