Anti-Human PRDX6 Polyclonal Antibody (HB999014)

Name: Anti-Human PRDX6 Polyclonal Antibody
Brand: abinScience
SKU: HB999014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

HB999014

Description

Anti-Human PRDX6 Polyclonal Antibody (HB999014) is a rabbit polyclonal antibody detecting PRDX6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PRDX6 (Met1-Pro224).

Target

24 kDa protein, Lysophosphatidylcholine acyltransferase 5, Acidic calcium-independent phospholipase A2, KIAA0106, LPCAT-5, 1-Cys PRX, Antioxidant protein 2, LPC acyltransferase 5, aiPLA2, Non-selenium glutathione peroxidase, Lyso-PC acyltransferase 5, PRDX6, AOP2, Glutathione-dependent peroxiredoxin, Peroxiredoxin-6, NSGPx, Red blood cells page spot 12, 1-Cys peroxiredoxin, Liver 2D page spot 40

Purification

Purified by antigen affinity column.

Accession

P30041

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Peroxiredoxin-6 (PRDX6) is a ~25 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH. Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.

1. Chen, JW. et al. (2000) The Journal of biological chemistry 275, 28421-7. PMID: 10893423

2. Kang, SW. et al. (1998) The Journal of biological chemistry 273, 6303-11. PMID: 9497358

3. Fisher, AB. et al. (2016) Journal of lipid research 57, 587-96. PMID: 26830860

Note

For research use only.

Images

References

Datasheet

Anti-Human PRDX6 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PRDX6 Polyclonal Antibody (HB999014)

Overview

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References

Datasheet

SDS

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