

| Catalog No. | HP541014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SRXN1 Polyclonal Antibody (HP541014) is a rabbit polyclonal antibody detecting SRXN1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SRXN1 (His42-Gln137). | ||||||||
| Target | Sulfiredoxin-1, SRXN1, C20orf139, SRX, SRX1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9BYN0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Sulfiredoxin-1 (SRXN1) is a ~14 kDa protein. Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. 1. Chang, TS. et al. (2004) The Journal of biological chemistry 279, 50994-1001. PMID: 15448164 2. Woo, HA. et al. (2005) The Journal of biological chemistry 280, 3125-8. PMID: 15590625 | ||||||||
| Note | For research use only. |
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