Anti-Human WDR46 Polyclonal Antibody (HT164014)

Name: Anti-Human WDR46 Polyclonal Antibody
Brand: abinScience
SKU: HT164014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HT164014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human WDR46 (Lys187-Glu523).

Target

WDR46, C6orf11, BING4, WD repeat-containing protein BING4, WD repeat-containing protein 46

Purification

Purified by antigen affinity column.

Accession

O15213

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

WD repeat-containing protein 46 (WDR46) is a ~68 kDa protein. Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.

1. Hirai, Y. et al. (2013) Genes to cells : devoted to molecular & cellular mechanisms 18, 780-97. PMID: 23848194

2. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-WDR46 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Hela cell lysate

References

Datasheet

Anti-Human WDR46 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human WDR46 Polyclonal Antibody (HT164014)

Overview

Images

References

Datasheet

SDS

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