

| Catalog No. | HB050014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SLC2A5 (Pro461-Gln501). | ||||||||
| Target | SLC2A5, GLUT-5, Glucose transporter type 5, small intestine, GLUT5, Solute carrier family 2, facilitated glucose transporter member 5, Fructose transporter | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P22732 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Solute carrier family 2, facilitated glucose transporter member 5 (SLC2A5) is a ~54 kDa protein. Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake. 1. Manolescu, A. et al. (2005) The Journal of biological chemistry 280, 42978-83. PMID: 16186102 2. Manolescu, AR. et al. (2007) Molecular membrane biology 24, 455-63. PMID: 17710649 3. Ebert, K. et al. (2017) The Journal of membrane biology 250, 171-182. PMID: 28083649 4. Gauer, JS. et al. (2018) Biochemical pharmacology 152, 11-20. PMID: 29548810 5. Rand, EB. et al. (1993) The American journal of physiology 264, G1169-76. PMID: 8333543 6. Kayano, T. et al. (1990) The Journal of biological chemistry 265, 13276-82. PMID: 1695905 | ||||||||
| Note | For research use only. |
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