

| Catalog No. | HP773014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human POLDIP2 (Gly80-Trp368). | ||||||||
| Target | Polymerase delta-interacting protein 2, p38, 38 kDa DNA polymerase delta interaction protein, POLDIP2, PDIP38, POLD4 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9Y2S7 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Polymerase delta-interacting protein 2 (POLDIP2) is a ~42 kDa protein. Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1). 1. Maga, G. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 18850-5. PMID: 24191025 2. Guilliam, TA. et al. (2016) Nucleic acids research 44, 3317-29. PMID: 26984527 | ||||||||
| Note | For research use only. |
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