Anti-Human RCOR1 Polyclonal Antibody (HP659014)

Name: Anti-Human RCOR1 Polyclonal Antibody
Brand: abinScience
SKU: HP659014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP659014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RCOR1 (Asn141-Glu266).

Target

RCOR1, REST corepressor 1, RCOR, Protein CoREST, KIAA0071

Purification

Purified by antigen affinity column.

Accession

Q9UKL0

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

REST corepressor 1 (RCOR1) is a ~53 kDa protein. Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-RCOR1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Molt-4 cell lysate
Lane 2: HT-29 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Mouse testis lysate
Lane 5: Rat brain lysate

References

Datasheet

Anti-Human RCOR1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

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Anti-Human RCOR1 Polyclonal Antibody (HP659014)

Overview

Images

References

Datasheet

SDS

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