Anti-Human ABCA7 Polyclonal Antibody (HP315014)

Name: Anti-Human ABCA7 Polyclonal Antibody
Brand: abinScience
SKU: HP315014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HP315014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ABCA7 (Asp1773-Asp2121).

Target

Macrophage ABC transporter, ABCA-SSN, ATP-binding cassette sub-family A member 7, Autoantigen SS-N, Phospholipid-transporting ATPase ABCA7, ABCA7

Purification

Purified by antigen affinity column.

Accession

Q8IZY2

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Phospholipid-transporting ATPase ABCA7 is a ~234 kDa protein. Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Transports preferentially phosphatidylserine over phosphatidylcholine. Plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux.

1. Quazi, F. et al. (2013) The Journal of biological chemistry 288, 34414-26. PMID: 24097981

2. Wang, N. et al. (2003) The Journal of biological chemistry 278, 42906-12. PMID: 12917409

3. Kielar, D. et al. (2003) The Journal of investigative dermatology 121, 465-74. PMID: 12925201

4. Abe-Dohmae, S. et al. (2004) The Journal of biological chemistry 279, 604-11. PMID: 14570867

5. Ikeda, Y. et al. (2003) Biochemical and biophysical research communications 311, 313-8. PMID: 14592415

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human ABCA7 polyclonal antibody at 1ug/mL on recombinant Human ABCA7 (Catalog No. HP315012).

References

Datasheet

Anti-Human ABCA7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human ABCA7 Polyclonal Antibody (HP315014)

Overview

Images

References

Datasheet

SDS

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