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Anti-Human TRPC1 Polyclonal Antibody (HW754014)

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Overview
Catalog No.HW754014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human TRPC1 (Thr45-Lys386).
Target TRPC1, TRP-1, TRP1, TrpC1, Short transient receptor potential channel 1, Transient receptor protein 1
Purification Purified by antigen affinity column.
Accession P48995
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Short transient receptor potential channel 1 (TRPC1) is a ~91 kDa protein. Forms a receptor-activated non-selective calcium permeant cation channel. Forms a heteromeric ion channel with TRPC4 or TRPC5 that has reduced calcium permeability compared to the homomeric TRPC4 or TRPC5 channel. Also permeable to monovalent ions including sodium, lithium and cesium ions.

1. Xu, SZ. et al. (2001) Circulation research 88, 84-7. PMID: 11139478
2. Ahmmed, GU. et al. (2004) The Journal of biological chemistry 279, 20941-9. PMID: 15016832
3. Won, J. et al. (2025) Nature structural & molecular biology 32, 326-338. PMID: 39478185
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human TRPC1 Polyclonal Antibody

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