Anti-Human SNX5 Polyclonal Antibody (HP226014)

Name: Anti-Human SNX5 Polyclonal Antibody
Brand: abinScience
SKU: HP226014
Price: 96 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HP226014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SNX5 (Met1-Asp171).

Target

SNX5, Sorting nexin-5

Purification

Purified by antigen affinity column.

Accession

Q9Y5X3

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Sorting nexin-5 (SNX5) is a ~46 kDa protein. Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).

1. Merino-Trigo, A. et al. (2004) Journal of cell science 117, 6413-24. PMID: 15561769

2. van Weering, JR. et al. (2012) The EMBO journal 31, 4466-80. PMID: 23085988

3. Wassmer, T. et al. (2007) Journal of cell science 120, 45-54. PMID: 17148574

4. Hara, S. et al. (2008) Molecular biology of the cell 19, 3823-35. PMID: 18596235

5. Sun, Y. et al. (2013) Developmental cell 25, 144-55. PMID: 23602387

6. Schill, NJ. et al. (2014) Journal of cell science 127, 2189-203. PMID: 24610942

7. Lim, JP. et al. (2008) BMC cell biology 9, 58. PMID: 18854019

8. Wang, JT. et al. (2010) PloS one 5, e13763. PMID: 21048941

Note

For research use only.

Images

References

Datasheet

Anti-Human SNX5 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-Human SNX5 Polyclonal Antibody (HP226014)

Overview

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References

Datasheet

SDS

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