

| Catalog No. | HP671014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ZBTB18 (Met1-Thr128). | ||||||||
| Target | Zinc finger and BTB domain-containing protein 18, RP58, TAZ1, ZNF238, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger protein C2H2-171, Zinc finger protein 238, ZBTB18, 58 kDa repressor protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q99592 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Zinc finger and BTB domain-containing protein 18 (ZBTB18) is a ~58 kDa protein. Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus. | ||||||||
| Note | For research use only. |
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