Anti-Human KHDRBS1 Polyclonal Antibody (HC692014)

Name: Anti-Human KHDRBS1 Polyclonal Antibody
Brand: abinScience
SKU: HC692014
Price: 168 USD
Availability: InStock

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Spec:

50ug
100ug

Number:

Overview
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References
Datasheet

Overview

Catalog No.

HC692014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human KHDRBS1 (Lys111-Gly276).

Target

p21 Ras GTPase-activating protein-associated p62, GAP-associated tyrosine phosphoprotein p62, KH domain-containing, RNA-binding, signal transduction-associated protein 1, SAM68, p68, Sam68, KHDRBS1, Src-associated in mitosis 68 kDa protein

Purification

Purified by antigen affinity column.

Accession

Q07666

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) is a ~48 kDa protein. Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

1. Rajanala, K. et al. (2012) PloS one 7, e29921. PMID: 22253824

2. Nakka, KK. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, E3374-83. PMID: 26080397

3. Paronetto, MP. et al. (2007) The Journal of cell biology 176, 929-39. PMID: 17371836

4. Pedrotti, S. et al. (2010) The EMBO journal 29, 1235-47. PMID: 20186123

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human KHDRBS1 polyclonal antibody at 1ug/mL on recombinant Human KHDRBS1 (Catalog No. HC692012).

References

Datasheet

Anti-Human KHDRBS1 Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human KHDRBS1 Polyclonal Antibody (HC692014)

Overview

Images

References

Datasheet

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