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Anti-Human OSBPL2 Polyclonal Antibody (HP845014)

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Overview
Catalog No.HP845014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human OSBPL2 (Ala96-Asp325).
Target ORP-2, Oxysterol-binding protein-related protein 2, ORP2, OSBPL2, KIAA0772, OSBP-related protein 2
Purification Purified by antigen affinity column.
Accession Q9H1P3
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Oxysterol-binding protein-related protein 2 (OSBPL2) is a ~55 kDa protein. Intracellular transport protein that binds sterols and phospholipids and mediates lipid transport between intracellular compartments. Increases plasma membrane cholesterol levels and decreases phosphatidylinositol-4,5-bisphosphate levels in the cell membrane. Binds phosphoinositides, such as phosphatidylinositol-4,5-bisphosphate. Exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate. Binds cholesterol, dehydroergosterol, 22(R)-hydroxycholesterol and 25-hydroxycholesterol (in vitro).

1. Wang, H. et al. (2019) Molecular cell 73, 458-473.e7. PMID: 30581148
2. Xu, Y. et al. (2001) The Journal of biological chemistry 276, 18407-14. PMID: 11279184
3. Suchanek, M. et al. (2007) The Biochemical journal 405, 473-80. PMID: 17428193
4. Hynynen, R. et al. (2009) Journal of lipid research 50, 1305-15. PMID: 19224871
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human OSBPL2 Polyclonal Antibody

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