Anti-Human CES1 Polyclonal Antibody (HB693014)

Name: Anti-Human CES1 Polyclonal Antibody
Brand: abinScience
SKU: HB693014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB693014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CES1 (Gly18-Leu299).

Target

Serine esterase 1, Monocyte/macrophage serine esterase, Retinyl ester hydrolase, Liver carboxylesterase 1, REH, Methylumbelliferyl-acetate deacetylase 1, HMSE, ACAT, hCE-1, Acyl-coenzyme A:cholesterol acyltransferase, CE-1, Brain carboxylesterase hBr1, CEH, SES1, CES2, Cholesteryl ester hydrolase, Triacylglycerol hydrolase, Cocaine carboxylesterase, TGH, Carboxylesterase 1, CES1, Egasyn

Purification

Purified by antigen affinity column.

Accession

P23141

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Liver carboxylesterase 1 (CES1) is a ~62 kDa protein. Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.

1. Crow, JA. et al. (2008) Biochimica et biophysica acta 1781, 643-54. PMID: 18762277

2. Brzezinski, MR. et al. (1994) Biochemical pharmacology 48, 1747-55. PMID: 7980644

3. Pindel, EV. et al. (1997) The Journal of biological chemistry 272, 14769-75. PMID: 9169443

4. Schindler, R. et al. (1998) European journal of biochemistry 251, 863-73. PMID: 9490062

5. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Human CES1 polyclonal antibody at 1ug/mL on recombinant Human CES1 (Catalog No. HB693012).

References

Datasheet

Anti-Human CES1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CES1 Polyclonal Antibody (HB693014)

Overview

Images

References

Datasheet

SDS

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