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Anti-FBLN5 Polyclonal Antibody (HV610014)

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Overview
Catalog No.HV610014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human FBLN5 (Leu99-Cys205).
Target UP50, Urine p50 protein, DANCE, Fibulin-5, Developmental arteries and neural crest EGF-like protein, Dance, FBLN5, FIBL-5
Purification Purified by antigen affinity column.
Accession Q9UBX5
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Fibulin-5 (FBLN5) is a ~50 kDa protein. Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN.

1. Claus, S. et al. (2008) The Journal of investigative dermatology 128, 1442-50. PMID: 18185537
2. Nakamura, T. et al. (1999) The Journal of biological chemistry 274, 22476-83. PMID: 10428823
3. El-Hallous, E. et al. (2007) The Journal of biological chemistry 282, 8935-46. PMID: 17255108
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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