Anti-TRPC6 Polyclonal Antibody (HV333014)

Name: Anti-TRPC6 Polyclonal Antibody
Brand: abinScience
SKU: HV333014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HV333014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human TRPC6 (Met1-Leu192).

Target

TrpC6, TRP-6, Short transient receptor potential channel 6, Transient receptor protein 6, TRP6, TRPC6

Purification

Purified by antigen affinity column.

Accession

Q9Y210

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Short transient receptor potential channel 6 (TRPC6) is a ~106 kDa protein. Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Does not seem to be activated by intracellular calcium store depletion.

1. Heeringa, SF. et al. (2009) PloS one 4, e7771. PMID: 19936226

2. Hofstra, JM. et al. (2013) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 28, 1830-8. PMID: 23291369

3. Riehle, M. et al. (2016) Journal of the American Society of Nephrology : JASN 27, 2771-83. PMID: 26892346

4. Hofmann, T. et al. (1999) Nature 397, 259-63. PMID: 9930701

Note

For research use only.

Images

References

Datasheet

Anti-TRPC6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-TRPC6 Polyclonal Antibody (HV333014)

Overview

Images

References

Datasheet

SDS

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