

| Catalog No. | HT198014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human RS1 (Ser24-Ala224). | ||||||||
| Target | RS1, X-linked juvenile retinoschisis protein, XLRS1, Retinoschisin | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O15537 | ||||||||
| RRID | Anti-RS1 Polyclonal Antibody (abinScience Cat# HT198014, RRID:AB_3722815) |
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| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Retinoschisin (RS1) is a ~25 kDa protein. Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides. May play a role in cell-cell adhesion processes in the retina, via homomeric interaction between octamers present on the surface of two neighboring cells. Required for normal structure and function of the retina. 1. Tolun, G. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5287-92. PMID: 27114531 2. Lesch, B. et al. (2008) Molecular vision 14, 2321-32. PMID: 19093009 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-RS1 polyclonal antibody at 1ug/mL on recombinant RS1 (Catalog No. HT198012).
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