

| Catalog No. | HY098014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human EPB41 (Met210-Lys497). | ||||||||
| Target | Band 4.1, EPB4.1, Protein 4.1, 4.1R, EPB41, P4.1, E41P, Erythrocyte membrane protein band 4.1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P11171 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Protein 4.1 (EPB41) is a ~97 kDa protein. Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase. 1. Kiyomitsu, T. et al. (2013) Cell 154, 391-402. PMID: 23870127 | ||||||||
| Note | For research use only. |
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