Anti-BCL11A Polyclonal Antibody (HP181014)

Name: Anti-BCL11A Polyclonal Antibody
Brand: abinScience
SKU: HP181014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HP181014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human BCL11A (Met1-Arg210).

Target

B-cell CLL/lymphoma 11A, EVI-9, CTIP1, EVI9, Zinc finger protein 856, KIAA1809, B-cell lymphoma/leukemia 11A, COUP-TF-interacting protein 1, Ecotropic viral integration site 9 protein homolog, ZNF856, BCL11A, BCL-11A

Purification

Purified by antigen affinity column.

Accession

Q9H165

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

BCL11 transcription factor A (BCL11A) is a ~91 kDa protein. Transcription factor. Associated with the BAF SWI/SNF chromatin remodeling complex. Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene. Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin (HbF) level. Involved in brain development.

1. Liu, H. et al. (2006) Molecular cancer 5, 18. PMID: 16704730

2. Liu, N. et al. (2018) Cell 173, 430-442.e17. PMID: 29606353

3. Kadoch, C. et al. (2013) Nature genetics 45, 592-601. PMID: 23644491

4. Zheng, G. et al. (2024) Science (New York, N.Y.) 386, 1010-1018. PMID: 39607926

5. Viennet, T. et al. (2024) Structure (London, England : 1993) 32, 2276-2286.e4. PMID: 39423807

6. Bauer, DE. et al. (2015) Current opinion in genetics & development 33, 62-70. PMID: 26375765

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-BCL11A polyclonal antibody at 1ug/mL on recombinant BCL11A (Catalog No. HP181012).

References

Datasheet

Anti-BCL11A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-BCL11A Polyclonal Antibody (HP181014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us