Anti-Human CCL17/TARC Polyclonal Antibody (HV615014)

Name: Anti-Human CCL17/TARC Polyclonal Antibody
Brand: abinScience
SKU: HV615014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HV615014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CCL17/TARC (Ala24-Ser94).

Target

Thymus and activation-regulated chemokine, SCYA17, TARC, Small-inducible cytokine A17, C-C motif chemokine 17, CC chemokine TARC, CCL17

Purification

Purified by antigen affinity column.

Accession

Q92583

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Imai, T. et al. (1996) The Journal of biological chemistry 271, 21514-21. PMID: 8702936

2. Imai, T. et al. (1997) The Journal of biological chemistry 272, 15036-42. PMID: 9169480

3. Garlisi, CG. et al. (1999) European journal of immunology 29, 3210-5. PMID: 10540332

4. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438

Note

For research use only.

Images

References

Datasheet

Anti-Human CCL17/TARC Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CCL17/TARC Polyclonal Antibody (HV615014)

Overview

Images

References

Datasheet

SDS

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