Anti-Human SRY Polyclonal Antibody (HC271014)

Name: Anti-Human SRY Polyclonal Antibody
Brand: abinScience
SKU: HC271014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HC271014

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SRY (Met1-Leu204).

Target

TDF, Sex-determining region Y protein, Testis-determining factor, SRY

Purification

Purified by antigen affinity column.

Accession

Q05066

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Sex-determining region Y protein (SRY) is a ~23 kDa protein. Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.

1. Murphy, EC. et al. (2001) Journal of molecular biology 312, 481-99. PMID: 11563911

2. Oh, HJ. et al. (2006) Molecular and cellular endocrinology 247, 47-52. PMID: 16414182

3. Polanco, JC. et al. (2007) Developmental biology 302, 13-24. PMID: 16996051

4. Desclozeaux, M. et al. (1998) The Journal of biological chemistry 273, 7988-95. PMID: 9525897

5. Ferrari, S. et al. (1992) The EMBO journal 11, 4497-506. PMID: 1425584

6. Phillips, NB. et al. (2004) Biochemistry 43, 7066-81. PMID: 15170344

7. Giese, K. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 3368-72. PMID: 8159753

8. King, CY. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 11990-4. PMID: 8265659

Note

For research use only.

Images

References

Datasheet

Anti-Human SRY Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SRY Polyclonal Antibody (HC271014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us