Anti-Human DUT Polyclonal Antibody (HW698014)

Name: Anti-Human DUT Polyclonal Antibody
Brand: abinScience
SKU: HW698014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW698014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human DUT (Met112-Asn252).

Target

dUTP pyrophosphatase, DUT, dUTPase, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

Purification

Purified by antigen affinity column.

Accession

P33316

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) is a ~26 kDa protein. Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation into DNA and at the same time provides dUMP, the substrate for de novo thymidylate biosynthesis. Inhibits peroxisome proliferator-activated receptor (PPAR) activity by binding of its N-terminal to PPAR, preventing the latter's dimerization with retinoid X receptor. Essential for embryonic development.

1. Varga, B. et al. (2007) FEBS letters 581, 4783-8. PMID: 17880943

2. Ladner, RD. et al. (1996) The Journal of biological chemistry 271, 7745-51. PMID: 8631816

3. Mol, CD. et al. (1996) Structure (London, England : 1993) 4, 1077-92. PMID: 8805593

Note

For research use only.

Images

References

Datasheet

Anti-Human DUT Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human DUT Polyclonal Antibody (HW698014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us