

| Catalog No. | HW764014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human PEX19 (Glu98-His263). | ||||||||
| Target | Peroxisomal biogenesis factor 19, Peroxisomal farnesylated protein, Peroxin-19, PEX19, PXF, 33 kDa housekeeping protein, HK33 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P40855 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Peroxisomal biogenesis factor 19 (PEX19) is a ~32 kDa protein. Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53. | ||||||||
| Note | For research use only. |
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