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Anti-Human AKAP1 Polyclonal Antibody (HP035014)

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Overview
Catalog No.HP035014
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human AKAP1 (Asp606-Leu903).
Target PRKA1, S-AKAP84, AKAP149, AKAP 149, Protein kinase A-anchoring protein 1, D-AKAP-1, Dual specificity A-kinase-anchoring protein 1, AKAP1, Spermatid A-kinase anchor protein 84, A-kinase anchor protein 149 kDa, A-kinase anchor protein 1, mitochondrial
Purification Purified by antigen affinity column.
Accession Q92667
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

A-kinase anchor protein 1, mitochondrial (AKAP1) is a ~97 kDa protein. Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane. Involved in mitochondrial-mediated antiviral innate immunity. Promotes translocation of NDUFS1 into mitochondria to regulate mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) activity.

1. Yoshinaka, T. et al. (2019) iScience 19, 1065-1078. PMID: 31522117
Note For research use only.
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Formula
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Anti-Human AKAP1 Polyclonal Antibody

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