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Anti-Human GOLGA1 Polyclonal Antibody (HP495014)

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Overview
Catalog No.HP495014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human GOLGA1 (Leu687-Gly746).
Target GOLGA1, Golgin subfamily A member 1, Golgin-97
Purification Purified by antigen affinity column.
Accession Q92805
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Golgin subfamily A member 1 (GOLGA1) is a ~88 kDa protein. Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. Mechanistically, captures transport vesicles arriving from endosomes via the protein TBC1D23. Recognized vesicles are then tethered to the trans-Golgi before subsequent SNARE engagement and vesicle fusion. Selectively regulates E-cadherin transport from the trans-Golgi network in tubulovesicular carriers.

1. Shin, JJH. et al. (2017) Nature cell biology 19, 1424-1432. PMID: 29084197
2. Cattin-Ortolá, J. et al. (2024) Science advances 10, eadl0608. PMID: 38552021
3. Grimaldi, G. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119. PMID: 34969853
Note For research use only.
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