Anti-Human RANBP9 Polyclonal Antibody (HP154014)

Name: Anti-Human RANBP9 Polyclonal Antibody
Brand: abinScience
SKU: HP154014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HP154014

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human RANBP9 (Ser176-Gly330).

Target

RanBP7, RanBPM, RanBP9, Ran-binding protein 9, Ran-binding protein M, BPM90, RANBP9, BPM-L, RANBPM

Purification

Purified by antigen affinity column.

Accession

Q96S59

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ran-binding protein 9 (RANBP9) is a ~77 kDa protein. May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway.

1. Valiyaveettil, M. et al. (2008) The Journal of cell biology 182, 727-39. PMID: 18710924

2. Lampert, F. et al. (2018) eLife 7. PMID: 29911972

3. Denti, S. et al. (2004) The Journal of biological chemistry 279, 13027-34. PMID: 14722085

4. Wang, D. et al. (2002) The Journal of biological chemistry 277, 36216-22. PMID: 12147692

5. Rao, MA. et al. (2002) The Journal of biological chemistry 277, 48020-7. PMID: 12361945

6. Harada, N. et al. (2008) Biochemical and biophysical research communications 368, 121-5. PMID: 18222118

7. Kramer, S. et al. (2005) Oncogene 24, 938-44. PMID: 15558019

Note

For research use only.

Images

References

Datasheet

Anti-Human RANBP9 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RANBP9 Polyclonal Antibody (HP154014)

Overview

Images

References

Datasheet

SDS

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