

| Catalog No. | HP524014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human CRNN (Met1-Gly95). | ||||||||
| Target | SEP53, DRC1, Tumor-related protein, CRNN, 58 kDa heat shock protein, 53 kDa putative calcium-binding protein, C1orf10, PDRC1, 53 kDa squamous epithelial-induced stress protein, Squamous epithelial heat shock protein 53, Cornulin | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UBG3 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Cornulin (CRNN) is a ~53 kDa protein. Promotes cell proliferation, G1/S cell cycle progression and induces expression of the cell cycle regulator CCND1. Regulates proliferation induced by pro-inflammatory cytokine response via activation of NFKB1 and PI3K/AKT signaling pathways. 1. Li, C. et al. (2019) The Journal of investigative dermatology 139, 71-80. PMID: 30009832 | ||||||||
| Note | For research use only. |
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