Anti-MARV GP1/Envelope glycoprotein 1 Polyclonal Antibody (VK669014)

Name: Anti-MARV GP1/Envelope glycoprotein 1 Polyclonal Antibody
Brand: abinScience
SKU: VK669014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK669014

Species reactivity

Lake Victoria marburgvirus (MARV) (Marburg virus)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant MARV GP1/Envelope glycoprotein 1 (Leu19-Gln205).

Target

Envelope glycoprotein, GP1, 2, GP, Virion spike glycoprotein, GP1, GP2, GP

Purification

Purified by antigen affinity column.

Accession

Q1PDC7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelope glycoprotein (GP1/Envelope glycoprotein 1) is a ~75 kDa protein. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection).

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-MARV GP1/Envelope glycoprotein 1 polyclonal antibody at 1ug/mL on recombinant MARV GP1/Envelope glycoprotein 1 (Catalog No. VK669012).

References

Datasheet