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Anti-Human MXD1 Polyclonal Antibody (HC460014)

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Overview
Catalog No.HC460014
Description
Anti-Human MXD1 Polyclonal Antibody (HC460014) is a rabbit polyclonal antibody detecting MXD1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human MXD1 (Met1-Ser145).
Target Protein MAD, MXD1, MAD, Max dimerizer 1, Max dimerization protein 1
Purification Purified by antigen affinity column.
Accession Q05195
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Max dimerization protein 1 (MXD1) is a ~25 kDa protein. Component of a transcriptional repressor complex together with MAX. In complex with MAX binds to the core DNA sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing with MYC for MAX binding. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.

1. Ayer, DE. et al. (1993) Cell 72, 211-22. PMID: 8425218
2. Lin, SY. et al. (2003) Cell 113, 881-9. PMID: 12837246
Note For research use only.
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Formula
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Working Solution
C₂ (Working Conc.)
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Anti-Human MXD1 Polyclonal Antibody

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