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Anti-Human JADE1 Polyclonal Antibody (HA939014)

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Overview
Catalog No.HA939014
Description
Anti-Human JADE1 Polyclonal Antibody (HA939014) is a rabbit polyclonal antibody detecting JADE1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human JADE1 (Gly217-Ser363).
Target KIAA1807, Jade family PHD finger protein 1, JADE1, PHD finger protein 17, Protein Jade-1, PHF17
Purification Purified by antigen affinity column.
Accession Q6IE81
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Protein Jade-1 (JADE1) is a ~95 kDa protein. Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.

1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653
2. Saksouk, N. et al. (2009) Molecular cell 33, 257-65. PMID: 19187766
3. Miotto, B. et al. (2010) Molecular cell 37, 57-66. PMID: 20129055
4. Lalonde, ME. et al. (2013) Genes & development 27, 2009-24. PMID: 24065767
5. Panchenko, MV. et al. (2004) The Journal of biological chemistry 279, 56032-41. PMID: 15502158
6. Zhou, MI. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 11035-40. PMID: 16046545
7. Borgal, L. et al. (2012) The Journal of biological chemistry 287, 25370-80. PMID: 22654112
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human JADE1 Polyclonal Antibody

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