

| Catalog No. | HA256014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human PDSS2 Polyclonal Antibody (HA256014) is a rabbit polyclonal antibody detecting PDSS2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human PDSS2 (Ser143-Ser399). | ||||||||
| Target | All-trans-decaprenyl-diphosphate synthase subunit 2, Solanesyl-diphosphate synthase subunit 2, C6orf210, PDSS2, DLP1, Decaprenyl-diphosphate synthase subunit 2, Candidate tumor suppressor protein, All trans-polyprenyl-diphosphate synthase PDSS2, Decaprenyl pyrophosphate synthase subunit 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q86YH6 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | All trans-polyprenyl-diphosphate synthase PDSS2 is a ~44 kDa protein. Heterotetrameric enzyme that catalyzes the condensation of farnesyl diphosphate (FPP), which acts as a primer, and isopentenyl diphosphate (IPP) to produce prenyl diphosphates of varying chain lengths and participates in the determination of the side chain of ubiquinone. Supplies nona and decaprenyl diphosphate, the precursors for the side chain of the isoprenoid quinones ubiquinone-9 (Q9) and ubiquinone-10 (Q10) respectively. The enzyme adds isopentenyl diphosphate molecules sequentially to farnesyl diphosphate with trans stereochemistry. May play a role during cerebellar development. May regulate mitochondrial respiratory chain function. 1. Saiki, R. et al. (2005) The FEBS journal 272, 5606-22. PMID: 16262699 | ||||||||
| Note | For research use only. |
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