Anti-Human UBASH3B Polyclonal Antibody (HA110014)

Name: Anti-Human UBASH3B Polyclonal Antibody
Brand: abinScience
SKU: HA110014
Price: 168 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.

HA110014

Description

Anti-Human UBASH3B Polyclonal Antibody (HA110014) is a rabbit polyclonal antibody detecting UBASH3B in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human UBASH3B (Gln382-Asp626).

Target

Tyrosine-protein phosphatase STS1/TULA2, TULA-2, STS1, Suppressor of T-cell receptor signaling 1, Ubiquitin-associated and SH3 domain-containing protein B, Cbl-interacting protein p70, STS-1, T-cell ubiquitin ligand 2, KIAA1959, UBASH3B

Purification

Purified by antigen affinity column.

Accession

Q8TF42

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ubiquitin-associated and SH3 domain-containing protein B (UBASH3B) is a ~72 kDa protein. Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.

Note

For research use only.

Images

References

Datasheet

Anti-Human UBASH3B Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human UBASH3B Polyclonal Antibody (HA110014)

Overview

Images

References

Datasheet

SDS

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