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Anti-Human ELAC2 Polyclonal Antibody (HA333014)

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Overview
Catalog No.HA333014
Description
Anti-Human ELAC2 Polyclonal Antibody (HA333014) is a rabbit polyclonal antibody detecting ELAC2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ELAC2 (Ile483-Thr688).
Target Heredity prostate cancer protein 2, Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, HPC2, Ribonuclease Z 2, ELAC2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2
Purification Purified by antigen affinity column.
Accession Q9BQ52
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Zinc phosphodiesterase ELAC protein 2 (ELAC2) is a ~92 kDa protein. Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly.

1. Brzezniak, LK. et al. (2011) RNA biology 8, 616-26. PMID: 21593607
2. Bogenhagen, DF. et al. (2014) Cell metabolism 19, 618-29. PMID: 24703694
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Concentration
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human ELAC2 Polyclonal Antibody

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