

| Catalog No. | VK461014 | ||||||
|---|---|---|---|---|---|---|---|
| Description |
Anti-HPV16 L1/Major capsid Polyclonal Antibody L1 Polyclonal Antibody (VK461014) is a rabbit polyclonal antibody detecting Major capsid protein L1 in ELISA, IHC, WB.
Highlights
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| Species reactivity | Human papillomavirus 16 (HPV16) | ||||||
| Applications | ELISA, IHC, WB | ||||||
| Host species | Rabbit | ||||||
| Isotype | IgG | ||||||
| Clonality | Polyclonal | ||||||
| Immunogen | E. coli - derived recombinant HPV16 L1/Major capsid protein L1. | ||||||
| Tested applications | WB | ||||||
| Target | Major capsid protein L1, L1 | ||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||
| Purification | Purified by antigen affinity column. | ||||||
| Accession | P03101 | ||||||
| Form | Liquid | ||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Background | Major capsid protein L1 is a ~56 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. | ||||||
| Note | For research use only. |

Western blot analysis was performed using anti-HPC46-L1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant HPV16 L1/Major capsid protein L1 (Catalog No: VK461022)




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