Anti-Nipah virus M/Protein M Polyclonal Antibody (VK408014)

Name: Anti-Nipah virus M/Protein M Polyclonal Antibody
Brand: abinScience
SKU: VK408014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK408014

Description

Anti-Nipah virus M/Protein M Polyclonal Antibody (VK408014) is a rabbit polyclonal antibody detecting Protein M in ELISA, IHC, WB. Suitable for Nipah virus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Nipah virus

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Nipah virus M/Protein M (Met1-Gly352).

Target

Matrix protein, Protein M, M

Purification

Purified by antigen affinity column.

Accession

Q9IK90

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Matrix protein (Protein M) is a ~39 kDa protein. Plays a crucial role in virion assembly and budding. Forms a shell at the inner face of the plasma membrane. Transits through the host nucleus before gaining the functional ability to localize and bud from the plasma membrane. Mediates together with fusion protein the incorporation of the glycoprotein to the viral particles. Also participates in the inhibition of the host interferon type I antiviral response by interacting with and thereby inhibiting host TRIM6.

1. Ciancanelli, MJ. et al. (2006) Journal of virology 80, 12070-8. PMID: 17005661

2. Patch, JR. et al. (2007) Virology journal 4, 1. PMID: 17204159

3. Patch, JR. et al. (2008) Virology journal 5, 137. PMID: 19000317

4. Wang, YE. et al. (2010) PLoS pathogens 6, e1001186. PMID: 21085610

5. Johnston, GP. et al. (2017) Journal of virology 91. PMID: 28250132

6. Bharaj, P. et al. (2016) PLoS pathogens 12, e1005880. PMID: 27622505

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-Nipah virus M/Protein M polyclonal antibody at 1ug/mL on recombinant Nipah virus M/Protein M (Catalog No. VK408012).

References

Datasheet