

| Catalog No. | VK819014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-RABV M/Matrix protein Polyclonal Antibody (VK819014) is a rabbit polyclonal antibody detecting Matrix protein in ELISA, IHC, WB.
Highlights
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| Species reactivity | Rabies virus (RABV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant RABV M/Matrix protein (Met1-Glu202). | ||||||||
| Target | Matrix protein, Phosphoprotein M2, M | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P16287 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Matrix protein is a ~23 kDa protein. Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons. Inhibits the integrated stress response (ISR) in the infected cell by blocking the formation of stress granules. 1. Liu, X. et al. (2021) The Journal of biological chemistry 296, 100096. PMID: 33208464 2. Finke, S. et al. (2003) The Journal of general virology 84, 1613-1621. PMID: 12771432 3. Mebatsion, T. et al. (1999) Journal of virology 73, 242-50. PMID: 9847327 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-RABV-M polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant RABV M/Matrix protein (Catalog No: VK819012)
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