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Anti-Human SOCS6 Polyclonal Antibody (HT133014)

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Overview
Catalog No.HT133014
Description
Anti-Human SOCS6 Polyclonal Antibody (HT133014) is a rabbit polyclonal antibody detecting SOCS6 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human SOCS6 (Thr370-Tyr535).
Target Suppressor of cytokine signaling 6, SOCS-6, Cytokine-inducible SH2 protein 4, CIS-4, Suppressor of cytokine signaling 4, SOCS-4, SOCS6, CIS4, SOCS4
Purification Purified by antigen affinity column.
Accession O14544
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Suppressor of cytokine signaling 6 (SOCS6) is a ~59 kDa protein. SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.

Note For research use only.
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Formula
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Anti-Human SOCS6 Polyclonal Antibody

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