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Anti-Human DEGS1 Polyclonal Antibody (HT403014)

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Overview
Catalog No.HT403014
Description
Anti-Human DEGS1 Polyclonal Antibody (HT403014) is a rabbit polyclonal antibody detecting DEGS1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human DEGS1 (Ile230-Glu323).
Target Sphingolipid delta(4)-desaturase DES1, 1.14.19.17, Cell migration-inducing gene 15 protein, Degenerative spermatocyte homolog 1, Dihydroceramide desaturase-1, Membrane lipid desaturase, Retinol isomerase, 5.2.1.-, DEGS1, DES1, MLD, MIG15
Purification Purified by antigen affinity column.
Accession O15121
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Sphingolipid delta(4)-desaturase DES1 (DEGS1) is a ~37 kDa protein. Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Catalyzes the equilibrium isomerization of retinols.

1. Ternes, P. et al. (2002) The Journal of biological chemistry 277, 25512-8. PMID: 11937514
2. Pant, DC. et al. (2019) The Journal of clinical investigation 129, 1240-1256. PMID: 30620337
3. Karsai, G. et al. (2019) The Journal of clinical investigation 129, 1229-1239. PMID: 30620338
Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human DEGS1 Polyclonal Antibody

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