

| Catalog No. | HF741014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human STK10 Polyclonal Antibody (HF741014) is a rabbit polyclonal antibody detecting STK10 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human STK10 (Asp31-Gly321). | ||||||||
| Target | Serine/threonine-protein kinase 10, 2.7.11.1, Lymphocyte-oriented kinase, STK10, LOK | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O94804 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Serine/threonine-protein kinase 10 (STK10) is a ~112 kDa protein. Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo. | ||||||||
| Note | For research use only. |
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