

| Catalog No. | HF982014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human NFATC1 Polyclonal Antibody (HF982014) is a rabbit polyclonal antibody detecting NFATc1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human NFATC1 (Ser423-Ile700). | ||||||||
| Target | Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2, NFATC | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | O95644 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1) is a ~101 kDa protein. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function. 1. Chuvpilo, S. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 162, 7294-301. PMID: 10358178 | ||||||||
| Note | For research use only. |
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