

| Catalog No. | HY551014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SNRNP70 Polyclonal Antibody (HY551014) is a rabbit polyclonal antibody detecting snRNP70 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SNRNP70 (Asp90-Glu221). | ||||||||
| Target | U1 small nuclear ribonucleoprotein 70 kDa, U1 snRNP 70 kDa, U1-70K, snRNP70, SNRNP70, RNPU1Z, RPU1, SNRP70, U1AP1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P08621 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70) is a ~51 kDa protein. Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. 1. Pomeranz Krummel, DA. et al. (2009) Nature 458, 475-80. PMID: 19325628 2. Kondo, Y. et al. (2015) eLife 4. PMID: 25555158 3. Query, CC. et al. (1989) Cell 57, 89-101. PMID: 2467746 | ||||||||
| Note | For research use only. |
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