Anti-Human SLC2A1 Polyclonal Antibody (HY199014)

Name: Anti-Human SLC2A1 Polyclonal Antibody
Brand: abinScience
SKU: HY199014
Price: 168 USD
Availability: InStock

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References
Datasheet
SDS

Overview

Catalog No.

HY199014

Description

Anti-Human SLC2A1 Polyclonal Antibody (HY199014) is a rabbit polyclonal antibody detecting SLC2A1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SLC2A1.

Target

Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, GLUT1

Purification

Purified by antigen affinity column.

Accession

P11166

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) is a ~54 kDa protein. Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation.

1. Klepper, J. et al. (1999) Neurochemical research 24, 587-94. PMID: 10227690

2. Woodrow, CJ. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 9931-6. PMID: 10954735

3. Mueckler, M. et al. (2008) The Journal of biological chemistry 283, 11550-5. PMID: 18245775

4. Mueckler, M. et al. (2009) Biochemistry 48, 5934-42. PMID: 19449892

5. Lee, EE. et al. (2015) Molecular cell 58, 845-53. PMID: 25982116

6. Kapoor, K. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 4711-6. PMID: 27078104

7. Jiang, X. et al. (2020) Cell 183, 258-268.e12. PMID: 32860739

Note

For research use only.

Images

References

Datasheet

Anti-Human SLC2A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human SLC2A1 Polyclonal Antibody (HY199014)

Overview

Images

References

Datasheet

SDS

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