Anti-Mouse CD79β/CD79B Polyclonal Antibody (MW431014)

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Datasheet

Overview

Catalog No.

MW431014

Description

Anti-Mouse CD79β/CD79B Polyclonal Antibody (MW431014) is a rabbit polyclonal antibody detecting CD79b in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD79β/CD79B (Val26-Ser145).

Target

B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, Cd79b, Igb

Purification

Purified by antigen affinity column.

Accession

P15530

RRID

Anti-Mouse CD79β/CD79B Polyclonal Antibody (abinScience Cat# MW431014, RRID:AB_3724718)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~25 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy).

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD79B polyclonal antibody at CD79B on various samples.
Lane 1: Daudi cell lysate
Lane 2: HL-60 cell lysate

References

Datasheet

Anti-Mouse CD79β/CD79B Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD79β/CD79B Polyclonal Antibody (MW431014)

Overview

Images

References

Datasheet

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