Anti-Mouse FPN1/SLC40A1/Ferroportin Polyclonal Antibody (MV370014)

Name: Anti-Mouse FPN1/SLC40A1/Ferroportin Polyclonal Antibody
Brand: abinScience
SKU: MV370014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

MV370014

Description

Anti-Mouse FPN1/SLC40A1/Ferroportin Polyclonal Antibody (MV370014) is a rabbit polyclonal antibody detecting Ferroportin-1 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse FPN1/SLC40A1/Ferroportin (Thr230-Pro306).

Target

Solute carrier family 40 member 1, Ferroportin-1, Iron-regulated transporter 1, Metal transporter protein 1, MTP1, Slc40a1, Fpn1, Ireg1, Slc11a3, Slc39a1

Purification

Purified by antigen affinity column.

Accession

Q9JHI9

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ferroportin (FPN1/SLC40A1) is a ~62 kDa protein. Transports Fe(2+) from the inside of a cell to the outside of the cell, playing a key role for maintaining systemic iron homeostasis. Transports iron from intestinal, splenic, hepatic cells, macrophages and erythrocytes into the blood to provide iron to other tissues. Controls therefore dietary iron uptake, iron recycling by macrophages and erythrocytes, and release of iron stores in hepatocytes. When iron is in excess in serum, circulating HAMP/hepcidin levels increase resulting in a degradation of SLC40A1, thus limiting the iron efflux to plasma.

1. Donovan, A. et al. (2005) Cell metabolism 1, 191-200. PMID: 16054062

2. Zhang, DL. et al. (2018) Blood 132, 2078-2087. PMID: 30213870

Note

For research use only.

Images

References

Datasheet

Anti-Mouse FPN1/SLC40A1/Ferroportin Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse FPN1/SLC40A1/Ferroportin Polyclonal Antibody (MV370014)

Overview

Images

References

Datasheet

SDS

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