Anti-Human RARB Polyclonal Antibody (HY385014)

Name: Anti-Human RARB Polyclonal Antibody
Brand: abinScience
SKU: HY385014
Price: 96 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

20ug
50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HY385014

Description

Anti-Human RARB Polyclonal Antibody (HY385014) is a rabbit polyclonal antibody detecting RARB in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RARB (Leu205-Ser451).

Target

Retinoic acid receptor beta, Nuclear receptor subfamily 1 group B member 2, RARB, HBV-activated protein, RAR-beta, RAR-epsilon, NR1B2, HAP

Purification

Purified by antigen affinity column.

Accession

P10826

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Retinoic acid receptor beta (RARB) is a ~50 kDa protein. Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element.

1. Hauksdottir, H. et al. (2003) Molecular endocrinology (Baltimore, Md.) 17, 373-85. PMID: 12554770

2. Chandra, V. et al. (2017) Nature communications 8, 868. PMID: 29021580

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-RARB polyclonal antibody at 1ug/mL on various samples.
Lane 1: HUVEC cell lysate
Lane 2: A431 cell lysate
Lane 3: A549 cell lysate

References

Datasheet

Anti-Human RARB Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human RARB Polyclonal Antibody (HY385014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us