Anti-RABV G/Glycoprotein Antibody (Fab094) (VK632053)

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Overview
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Datasheet

Overview

Catalog No.

VK632053

Description

Anti-RABV G/Glycoprotein Antibody (Fab094) [Fab094] (VK632053) is a mouse monoclonal antibody detecting Glycoprotein G in ELISA, IF, IP. Suitable for Rabies lyssavirus.

Highlights

●Multi-Application — Validated across multiple applications.

Species reactivity

Rabies lyssavirus, Rabies virus (strain CVS-11) (RABV)

Applications

ELISA, IF, IP

Host species

Mouse

Isotype

IgG1, kappa

Clone ID

Fab094

Clonality

Monoclonal

Target

G, Glycoprotein G

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O92284, A0A059WGD4

RRID

Anti-RABV G/Glycoprotein Antibody (Fab094) (abinScience Cat# VK632053, RRID:AB_3725364)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-RABV G/Glycoprotein Antibody (Fab094).

References

Datasheet

Anti-RABV G/Glycoprotein Antibody (Fab094).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-RABV G/Glycoprotein Antibody (Fab094) (VK632053)

Overview

Images

References

Datasheet

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