

| Catalog No. | JN073013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Anopheles stephensi | ||||
| Applications | Blocking, ELISA | ||||
| Host species | Mouse | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | 8H7 | ||||
| Clonality | Monoclonal | ||||
| Target | Aegyptin-like protein, Anopheline anti-platelet protein, AAPP, Anti-platelet aggregation protein, GE-rich salivary gland protein, AAPP, ansg-1 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | Q7YT37 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
| ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Aegyptin-like protein (Ansg-1) is a ~28 kDa protein. Modulates blood feeding of female mosquitoes on vertebrate hosts. Inhibits collagen-induced platelet aggregation in the host via preventing collagen interaction with its ligands: glycoprotein VI and integrin alpha-2/beta-1 (ITGA2/ITGB1). Inhibits collagen-induced increase of Ca(2+) levels in host platelets. Binds to host collagens. Binds Ca(2+). 1. Hayashi, H. et al. (2012) Thrombosis research 129, 169-75. PMID: 21986215 2. Islam, A. et al. (2019) Scientific reports 9, 3129. PMID: 30816309 3. Yoshida, S. et al. (2008) Blood 111, 2007-14. PMID: 18056842 4. Hayashi, H. et al. (2013) Platelets 24, 324-32. PMID: 22738392 5. Sugiyama, K. et al. (2014) The Journal of biological chemistry 289, 16303-12. PMID: 24764297 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Anopheles stephensi Ansg-1 Antibody (8H7)
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